Cisplatin and Nano-particle Formulations of Cisplatin for Cancer Therapy: A Review

Cisplatin (cis-(diammine)dichloridoplatinum(II)) is the first platinum-based compound approved by United States Food and Drug Administration (FDA) (U.S.). This a first-line chemotherapeutic treatment used alone or combined with other anticancer drugs to treat broad spectrum of malignancies, cisplatin-based nano-formulations currently in clinical studies. has several drawbacks, including low aqueous solubility, drug resistance, toxicity, all which can be addressed encapsulating Nemours nanocarriers. The various nano-delivery technologies developed for are covered vast literature from different electronic databases. review focuses on comparative findings over recent advancements, developments, innovations, updated CDDP nano-carrier systems.